Release:2016, Vol. 2. №3
About the authors:Elena V. Agbalian, Dr. Sci. (Biol.), Chief Researcher, Head of the Sector, Scientific Center for the Study of the Arctic (Nadym); email@example.com
A cytogenetic study of the residents of Yamal-Nenets Autonomous Area living in the regions with different levels of man-caused impact on the natural environment has been carried out. The study data is the medications of buccal exfoliated cells of Antipayuta villagers from Taz region and Nyda villagers from Nadym region, who were evaluated by microscopy. The research results show significant differences in the studied cytogenetic samples: the frequency of micronuclei cells, apoptotic index of late stages of core degradation, and accumulation index of cytogenetic abnormalities. Significant disturbances of cellular homeostasis in Nyda villagers by reducing the activity of apoptosis are indicated. The obtained data show the availability of cytogenetic markers to assess the impact of adverse environmental factors on the human body.