Influence of physical activity on sekretorny function of digestive glands and immune status of an organism

Tyumen State University Herald. Natural Resource Use and Ecology


2015, Vol. 1. №3(3)

Influence of physical activity on sekretorny function of digestive glands and immune status of an organism

About the authors:

Nina V. Sazhina, Cand. biol. Sci., associate professor, Kurgan State University
Aleksander P. Kuznetsov, Dr. Biol. Sci., Professor, Honoured Scientist of the Russian Federation, Head of Human Anatomy and Physiology Department, Kurgan State
Lada N. Smelysheva, Dr. Med. Sci., Professor, Kurgan State University


In 28 males aged 18-24 years at rest and after bicycle exercise load capacity of 36900kg / m parallel investigated salivary, gastric, pancreas and the immune status of the organism. After physical exercise significantly increased (up to 154,6 ± 14,1%) the content of α-amylase in pancreatic juice secretion in basal conditions and up to 147, ± 18,1% under stimulated secretion. When injected into the duodenum 30ml. 0.5% solution of HCL pH of gastric juice increases from 1,96 ± 0,12 to 3,67 ± 0,47 (p<0,005). Physical activity significantly enhances the inhibitory effect on gastric secretion induced by administration of a 0.5% solution of hydrochloric acid in the duodenum. It was established that administration of 0.5 ml 30% HCL solution dvennadtsatipertsnuyu intestine resulted in a reduction of segmented neutrophils, regarding the content of T lymphocytes (CD 3 +) and helper-induced CD 4 + population, CD 8 +. The level of natural killer content autorosettes and serum IgM and complement by 50% hemodialysis significantly increased. Physical activity increased the level of pancreatic secretion and decreased the percentage of lymphocytes, the absolute number of T-lymphocytes, CD 3+, CD 4+, CD 20+, NK cells and index CD 4/CD 8.


1.             Cottone P. CRF System Recruitment Mediates Dark Side of Compulsive Eating // Proc. Nat. Acad. Sci. USA. 2009. Pp. 20016-20020.

2.             Gentle N. M. Interleukins and the Formation of the Immunological Response
in Malignant Growth // Allergology and immunology. 2000. Vol. 1. No 1. Pp. 45-60.

3.             Moran T. N. Gut Peptides in the Control of Food Intake // Int. J. Obesity. 2009. Pp. 7-10ю

4.             West N. P. The effect of Exercise on Innate Mucosal Immunity // Br. J. Sports Med. 2008. No 5. Pp. 22-28.

5.             Zakharova M. F. Vliyanie razlichnyih vidov fizicheskih nagruzok na pokazateli fermentativnoy aktivnosti limfotsitov perifericheskoy krovi sportsmenov [The Impact of Different Types of Physical Stress on the Performance of the Enzymatic Activity of Peripheral Blood Lymphocytes in Athletes] // 2012. No 1. P. 57-59. (In Russian)

6.             Korotko G. F. Fiziologiya sistemyi pischevareniya [Physiology of the Digestive System]. Krasnodar, 2009. 608 p. (In Russian)

7.             Kuznetsov A. P. Zheludochno-kishechnyiy trakt i stress [Gastrointestinal Tract and Stress]. Kurgan: Izd-vo KGU [Kurgan State University Publisher], 2004. 254 p. (In Russian)

8.             Kuznetsov A. P., Gryaznyh A. V., Sazhinа N. V. Fiziologiya immunnoy sistemyi [Physiology of the Immune System]. Kurgan: Izd-vo KGU [Kurgan State University Publisher], 2015. 150 p. (In Russian)

9.             Milman V. E. Stress i lichnostnyie faktoryi regulyatsii deyatelnosti [Stress and Personal Factors of Activity Regulation] // Stress i trevogi v sporte [Regulation of stress and anxiety in sport]. Moscow: Fizkultura i sport [Physical Education and Sports], 2015. Pp. 24-26. (In Russian)

10.         Sternin Yu. I., Knorring G. U. Osobennosti sostoyaniya immunnoy sistemyi pri sportivnoy deyatelnosti [Features of the Immune System During Sports Activity] // Lechaschiy vrach [Attending physician]. 2008. No 8. (In Russian)

11.         Stogniy V. I. Sposob opredeleniya aktivnosti lizotsima v slyune i syivorotke krovi [Method for Determining the Activity of Lysozyme in Saliva and Serum] // Lab. delo [Laboratory work]. 1989. No 6. Pp. 15-17. (In Russian)