The level of gonadal and gonadotropic hormones in some forms of female endocrine infertility

Tyumen State University Herald. Natural Resource Use and Ecology


Bulletin of Tyumen State University. Medico-Biological Sciences (№6). 2014

The level of gonadal and gonadotropic hormones in some forms of female endocrine infertility

About the authors:

Andrey W. Elifanov, Cand. Sci. (Biol.), Head of the Department of Human and Animal Anatomy and Physiology, University of Tyumen;

Olga N. Lepunova, Cand. Sci. (Biol.), Associate Professor, Department of Human and Animal Anatomy and Physiology, Institute of Biology, Tyumen State University;


IIn the Far North the human organism is constantly exposed to climatic, geophysical and cosmic factors. The study of the reproductive function of women is critical at present since women are the most sensitive population group. Women's health is influenced by unfavorable climatic and geographic factors as well as characteristics of employment. Considering this aspect, we carried out a survey of women with endocrine infertility living in Nizhnevartovsk and working in various branches of industry. A multi-aspect analysis of the parameters of their hormonal status was carried out: we determined concentration of luteinizing hormone and follicle-stimulating hormone in different phases of the menstrual cycle in women with endocrine infertility; established the dependence of progesterone and estradiol secretion from the phase of the menstrual cycle; and studied the dependence of blood levels of hormones from the season of the year as well as from professional occupation. The examined women with a menstrual cycle with luteal phase deficiency demonstrate significant increase in the concentration of luteinizing hormone in the blood serum during the follicular phase, women with anovulatory cycles show a steady increase in the concentration of luteinizing hormone throughout the cycle. Analysis of the seasonal changes of the endocrine profile in women reveal an increase in the concentration of follicle stimulating hormone in winter (in the first phase of the cycle) and an increase of LH level in the first phase of the ovarian cycle during the summer period.The endocrine profile parameters in the surveyed women are not dependent on their professional occupation.


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