Adaptational characteristics of erythron system during heat exposure

About the authors:

Yuri M. Zaharov, Dr. Sci. (Med.), Academician (Russian Academy of Sciences), Head of Normal Physiology Departament, South-Ural State Medical University (Chelyabinsk, Russia)
Igor Yu. Melnikov, Cand. Sci. (Med.), Associate Professor, Normal physiology Deptartament, South-Ural State Medical University (Chelyabinsk, Russia)
Alexander G. Rassokhin, Doct. Sci. (Med.), Professor

Abstract:

The results of experimental investigations of long thermal effects on metabolism and associated tissue oxygen inquiry, peripheral part of the erythron, intercellular and intermolecular relationships in hematopoietic tissue — in erythroblastic  islets in the bone — marrow morphofunctional erythron units. Prolonged exposure to heat leads to a decrease of erythropoiesis, bringing the number of erythrocytes due to a decrease in oxygen consumption of tissues. The last is realized by various mechanisms of increase the deposit of erythrocytes in the spleen; accelerated elimination of erythrocytes, low stability to hemolysis; reduction of erythropoietic properties of blood; decreased production of thyroid hormones; reproduction in erythroblastic of erythrocytes islets adapted to changes in homeostasis.

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